Lithium (Low-Dose)
Ultra-low dose (1–5 mg) lithium supplements distinct from high-dose psychiatric lithium carbonate. Some research suggests neuroprotective effects, BDNF increase, and mood stabilization — but human evidence is very limited.
An ingredient with still-limited research

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Effects reported in research
Ultra-low doses suggested to have neuroprotective effects and increase BDNF
Epidemiological studies report inverse correlation between drinking water lithium levels and suicide rates
Small studies examine mood stabilization and cognitive maintenance
Dosage & timing
- 1–5 mg/day (lithium orotate).
- This is less than 1/100th of the therapeutic dose of psychiatric lithium carbonate.
Cautions
- •High-dose (psychiatric) lithium is nephrotoxic and thyrotoxic; low-dose supplement risk is currently unknown.
- •Consult a doctor for kidney or thyroid conditions, diuretic use, or any psychiatric medications.
Supporting research
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