Glutamine supplementation in sport and exercise: A review in the field of immunology and cell biology
Cruzat V, Macedo Rogero M, Noel Keane K, Curi R, Newsholme P
Evidence is still building up
Summary
A review of glutamine supplementation in athletes and adults performing intense exercise, from an immunology and cell-biology standpoint. It notes that plasma glutamine falls after intense exercise (linked to transient immune suppression) and that glutamine helps maintain gut barrier function, while additional benefits are limited when protein intake is adequate. Direct strength or hypertrophy benefits are not confirmed across multiple RCTs.
Key findings
- 1
Plasma glutamine decreases after intense exercise, associated with transient immune suppression
- 2
Intestinal glutamine plays a key role in maintaining gut barrier function
- 3
Additional benefits are limited when adequate protein is consumed through a healthy diet
Related supplements
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GlutamineView in official storeSupport for intestinal barrier function (research on gut protection during intense exercise and post-surgery)
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