Hormonal responses and adaptations to resistance exercise and training
Kraemer WJ, Ratamess NA
Evidence is still building up
Summary
抵抗性運動に対するホルモン応答（テストステロン・成長ホルモン・コルチゾール・インスリン様成長因子）の包括的レビュー。コルチゾールは筋タンパク質の異化（分解）を促進し、慢性的な高コルチゾール状態は筋肥大の同化シグナルに拮抗する。一方、トレーニング由来の急性コルチゾール上昇は適切な回復で速やかに正常化し、長期的な問題は生じない。
Key findings
- 1
コルチゾールは糖新生・タンパク質異化を促進し、慢性的な高値状態は筋タンパク合成を有意に抑制する
- 2
筋トレによる急性コルチゾール上昇は生理的反応であり、適切な回復をとれば筋肥大への悪影響はほぼない
- 3
慢性的なストレス（仕事・睡眠不足・栄養不足）によるコルチゾール高値は筋肥大を阻害する重要因子
- 4
テストステロン/コルチゾール比（T/C比）が筋肥大の同化状態を反映する指標として使われる
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