Citrulline
A non-essential amino acid that acts as a nitric oxide precursor, promoting vasodilation and improving blood flow and oxygen delivery to muscles. Has comparatively strong evidence as a pre-workout. Most research uses the citrulline malate complex.
An ingredient with growing research

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Effects reported in research
Improved muscular endurance (increased repetitions confirmed in research)
Reduced post-exercise muscle soreness (DOMS)
Enhanced pump sensation through vasodilation
Support for high-intensity anaerobic performance
Dosage & timing
- 6–8 g as citrulline malate, or 3–6 g as L-citrulline.
- Take 30–60 minutes before exercise.
Cautions
- •No serious side effects currently reported.
- •If taking antihypertensive medication, consult a doctor as blood pressure may drop excessively.
Supporting research
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