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Supplements

Capsaicin

Evidence ratingModerate

The active compound in chili peppers. Activates TRPV1 receptors to stimulate the sympathetic nervous system, studied for thermogenesis enhancement and appetite suppression.

An ingredient with growing research

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Effects reported in research

May slightly increase resting energy expenditure via thermogenesis

Some research reports increased satiety and appetite suppression

Suggested enhancement of fat oxidation

Dosage & timing

  • 2–6 mg/day of capsaicin (or capssinoid equivalent).
  • Typically taken before meals.

Cautions

  • Strong GI irritant — use with caution if you have GI disorders or IBS.
  • May worsen GERD.
  • High doses risk gastric mucosal irritation.

Supporting research

Alternatives

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