Capsaicin
The active compound in chili peppers. Activates TRPV1 receptors to stimulate the sympathetic nervous system, studied for thermogenesis enhancement and appetite suppression.
An ingredient with growing research

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Effects reported in research
May slightly increase resting energy expenditure via thermogenesis
Some research reports increased satiety and appetite suppression
Suggested enhancement of fat oxidation
Dosage & timing
- 2–6 mg/day of capsaicin (or capssinoid equivalent).
- Typically taken before meals.
Cautions
- •Strong GI irritant — use with caution if you have GI disorders or IBS.
- •May worsen GERD.
- •High doses risk gastric mucosal irritation.
Supporting research
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