Niacin (Vitamin B3)
The acid form of vitamin B3. Functions as an energy metabolism cofactor; at high doses (1–3 g/day), studied for lipid-improving effects including HDL elevation, LDL reduction, and triglyceride lowering.
An ingredient with growing research
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Effects reported in research
May elevate HDL and lower LDL/triglycerides at high doses
Promotes peripheral blood flow via vasodilation (also causes flushing)
Contributes to energy metabolism as an NAD+ precursor
Dosage & timing
- Vitamin supplementation: 14–18 mg/day.
- Lipid management (medical use): 1,000–3,000 mg/day under medical supervision.
Cautions
- •High doses cause flushing (redness, burning sensation).
- •Extended-release forms carry higher hepatotoxicity risk.
- •High-dose use requires medical supervision.
- •May raise blood glucose in diabetics.
Supporting research
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